![]() ![]() Extremely good Confidential multi-threading, debugging, profiling & optimizations. Used Windows API, UNIX/LINUX ABI, wxWidgets Qt (v1.0 to v5.10), C++.NET (managed and hybrid applications), COM, DCOM, ActiveX, COM+, WinRT and CORBA, IDL, custom design high performance low level IPCs, SOAP and REST Web Services.Extremely proficient with profilers (especially for GCC and MSVC), compiler compilers, debuggers, static and dynamic code analyzers, librarians, beautifiers, several build processes, cross platform and cross compiler semantics.Have designed, implemented and maintained extremely large C++ systems, multi process/IPC, multi-threaded (several models), multi paradigm and with good isolation between logical and physical models. Fully aware of vendor specific language extensions for GCC (including C/C++ mixed applications and GCJ), MSVC (including managed code and WinRTcpp), BCC, Intel, Comeau (compiler front-ends) and SUN’s Forte.Work up to gcc 6.2.x and 7.3.x (generally bootstrap my own compilers). First class commercial software (several commercial development tools for Confidential scientific computing and enterprise expert systems for manufacturing, medical R&D, home automation and security, law enforcement first responder CAD, (civil, mechanical, atomic and aeronautic) engineering applied software, applied AI, GIS, CAD/CAM, FEA, big data, FEA (non - linear dynamics), large-scale, low-latency, embedded, high throughput and frequency, big data, machine learning, ai, IoT, home automation, system PROGRAMMING, framework grade, best embedded idioms, cross platforM, Windows, Mac OS, Linux, Android, IOS, various clouds and beyond. ![]() Architect, design and effectively implement “clean code” based solutions using the highest Software Engineering Standards including multi paradigm, advanced design patterns and algorithms.Perfect employer also believes that Software Manufacturing is Engineering and applies strict Engineering practices and accepted standards to development, shipping virtually error free products in time and budget, using TDD & S.O.L.I.D. Obtain a Senior Software Engineer / Architect (preferable remote) position.
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In 2009, Flickr announced a partnership with Getty Images in which selected users could submit photographs for stock photography usage and receive payment. ![]() ![]() At the same time, the set limit for free accounts was lifted. On March 2, 2009, Flickr added the facility to upload and view HD videos, and began allowing free users to upload normal-resolution video. On April 9, 2008, Flickr began allowing paid subscribers to upload videos, limited to 90 seconds in length and 150 MB in size. On December 13, 2006, upload limits on free accounts were increased to 100 MB a month (from 20 MB) and were removed from Flickr Pro accounts, which originally had a 2 GB per month limit. įlickr upgraded its services from " beta" to " gamma" status on May 16, 2006, the changes attracted positive attention from Lifehacker. On January 31, 2007, Flickr announced that "Old Skool" members (those who had joined before the Yahoo! acquisition) would be required to associate their account with a Yahoo! identity by Mato continue using the service. On May 3, 2007, Yahoo! announced that Yahoo! Photos would close down on September 20, 2007, after which all photos would be deleted users were encouraged to migrate to Flickr. During the week of Jto July 2, 2005, all content was migrated from servers in Canada to servers in the United States, and all resulting data became subject to United States federal law. The acquisition reportedly cost $22 million to $25 million. Yahoo! acquired Ludicorp and Flickr on March 20, 2005. In addition to being a popular website for users to share and embed personal photographs and an online community, in 2004, the service was widely used by photo researchers and by bloggers to host images that they embed in blogs and social media. Key features of Flickr not initially present are tags, marking photos as favorites, group photo pools and interestingness, for which a patent was granted. It was eventually dropped as Flickr's back-end systems evolved away from Game Neverending 's codebase. The successive evolutions focused more on the uploading and filing back-end for individual users and the chat room was buried in the site map. Įarly versions of Flickr focused on a chat room called FlickrLive, with real-time photo exchange capabilities. Flickr proved a more feasible project, and ultimately Game Neverending was shelved, Butterfield later launched a similar online game, Glitch, which was shut down on November 14, 2012. The service emerged from tools originally created for Ludicorp's Game Neverending, a web-based massively multiplayer online game. History įlickr was launched on Februby Ludicorp, a Vancouver-based company founded by Stewart Butterfield and Caterina Fake. For mobile users, Flickr has official mobile apps for iOS, Android, and an optimized mobile site. Registering an account also allows users to create a profile page containing photos and videos that the user has uploaded and also grants the ability to add another Flickr user as a contact. Photos and videos can be accessed from Flickr without the need to register an account, but an account must be made to upload content to the site. On August 5, 2011, the site reported that it was hosting more than 6 billion images. Īs of June 10, 2015, Flickr had a total of 112 million registered members and more than 3.5 million new images uploaded daily. It has changed ownership several times and has been owned by SmugMug since April 20, 2018. It was created by Ludicorp in 2004 and was a popular way for amateur and professional photographers to host high-resolution photos.
![]() Cookies do not contain any personal data, so that the protection of the private sphere remains secure. Other Cookies remain on your system until they are deleted. Most of the used Cookies are so-called “session-cookies” that are erased automatically after your visit. to make possible an easy navigation and to display the web page correctly. Cookies are used to optimize the web page and for a user-friendly design, i.e. a Cookie-ID, IP-address, type and version of the browser used, operating system) your computer can be recognised when the website is called up again. Cookies are little text files, which are stored locally in the temporary memory of your Internet browser. We reserve the right to check the Server-Logfiles retrospectively, when there are indications for an unlawful use or if we are obliged to do so by a prosecuting authority. This data is not attributable to an identifiable person and this data will not be merged with other data sources. Time of retrieval and visited web pages.When you access our web pages, general information is automatically collected (so-called Server-Logfiles), i.e. Otherwise, information that cannot be attributed to an identified or identifiable natural person is not personal data, such as the number of visitants of a website.ĭata processing means any operation, which is performed on personal data whether or not by automated means (such as collection, recording, organisation, structuring, storage, adaptation or alteration, retrieval, consultation, use, disclosure by transmission, dissemination or otherwise making available, alignment or combination, restriction, erasure or destruction). These are for example names, email addresses, IP-addresses or phone numbers. Personal data means any information relating to an identified or identifiable natural person (‘data subject’). KGĮ-Mail: questions and requests related to data protection, please contact: We hereby want to inform you about the nature, scope and purposes of the processing of personal data in accordance with data protection law such as the General Data Protection Regulation - GDPR (REGULATION (EU) 2016/679) as well as about rights of data subjects.ĪRI-Armaturen Albert Richter GmbH & Co. ![]() Resolved an issue where grenade fuses could expire faster while the Ballistic Shield was in use.Resolved an issue where the Tempest could gain an extra charge if an enemy was killed by a player-owned Seeker or Scorestreak.Resolved an issue that could lead to multiple purchases of an item if the player had the Specialist selection menu open during round transition.Players can no longer spend cash on purchasing max ammo when they currently have max ammo.Ghost Perk now properly works against the mode's auto-UAV sweep.Endurance Chaos Moshpit, Mercenary Capture Moshpit, and Safeguard added to Featured category.Hardcore Moshpit added to Featured category (first-time addition).Limited-time free-for-all with new rotating weapon selection, including the KAP 45 full-auto pistol. ![]() Blackjack's Gun Game added as Featured Playlist.Black Ops 4 Update 1.12 Patch Notes Multiplayer Again, these changes are only live on Xbox One and PS4, but come to PC next week. Below, we've outlined the rest of the more minor changes coming in update 1.12. Update 1.12 also adds the Barbarians special event-which was already live on PS4-to Xbox One and PC, allowing you to earn an additional 25 tiers of loot. The new Blackout gametype Ambush has also debuted on PS4 with the new update, and is scheduled to come to Xbox One and PC next week. The radius and effectiveness of concussion grenades has also been reduced, while the fuse time and damage of the cluster grenade has increased. Now Playing: Call Of Duty: Black Ops 4 Video Review - Big Changesįor Blackout, all three levels of armor are being nerfed, with level three armor no longer fully protecting you from explosives or melee attacks. By clicking 'enter', you agree to GameSpot's ![]() The pyromaniac ability should have stacked on the burn chance beyond 100%. If I can go on a tangent, there is lost potential here with some abilities. So, the game works fine in my opinion with restricting the burning of high level enemies. ![]() Red skull level monsters gain a massive 200% burn resistance on top of the 1.6% increase each level. Higher level enemies do gain higher burn resistance (1.6% per level). I see nothing wrong with it as it stands for lower NPCs where they present less and less of a challenge and seeing Witcher Hunters turn to a crisp never gets boring. Plus primary Igni gives the AOE effect and Burn to multiple enemies and there was little to no benefit to using the alt form. In the end I didn't even take the alt Igni because it has a short range and any interruption loses the stamina cost right away. It also means you can use Igni in these situations but are taking an increasingly higher risk that they simply resist the Burn DOT. What they should have added to the game was a form of resistance to DOTs so that once an NPC is 1-2-3 levels above you they have a good chance to resist the Burn so it becomes less OP for higher level NPCs. It did feel rather unbalanced in those key fights for Sign builds to have no real options for these fights other than utility. I did do them all eventually but probably would have respecced against Eredin except for the use of Archgriffen decoction allowing simple strong hits to take 10% health. You are basically forced to either chip away really slowly as nothing is enhanced with melee or respec to a sword spec. This is really highlighted when you get to the three main boss fights towards the end of the game where Signs are all but useless and having a pure Sign build is a real disadvantage it takes forever to kill them as your melee is not specced at all. But it's not effective against quite a few other enemies. Primary Igni with burn becomes rather crazy against multiple humans and some other NPCs once Burn is built up. ![]() I had a Ingi/Quen/Axi/Ydren pure Sign build and it worked well for much of the long play through. What the game needs is some form of chance to resist DOT effects like Burn as NPCs become higher level compared to the player. Generally a Sign build including igni can be effective but not against all NPCs. ![]() However I feel that if those few tweaks were added it would be worth even more and it wouldn’t be debated. This is definitely more than two things □ but currently AS IS this app is a complete product is worthy of its asking price. I would like the option to highlight over pictures as well so I’m able to simulate lighting on my subjects. The Apple Pencil support is BEAUTIFUL! It would be nice to get some smudging features and paint for it. when I create a scene I want to be able to take a picture of my scenes and props and arrange them within Notability. The second feature that I would like to see, is a lasso tool for images. I use Notability for creating story boards and if I can have audio cue in correlation to my my scene breakdowns I would make more practical use of the audio player. Two features that I would love to see come to Notability is to be able to pin audio to a page visually, with a play button and a slider. People could complain but at least they’d have the option. My advice is to throw in a lifetime deal for like $50. I’m not a fan of the subscription model I would rather pay an obscene price one time instead of having an app potentially affect me in the future. I’m very happy with the usability of it in comparison to other note taking apps. I love Notability it is almost everything I’ve ever wanted. Privacy policy and terms of service available on Overall User Satisfaction Rating Manage subscription in account settings after purchase Subscription auto-renews unless cancelled, and will be charged via Apple iTunes account on an annual basis Premium content like academic planners, journals, stickers, and much more with a Notability subscription MyScript Handwriting Recognition and Math Conversion technology with a Notability subscription Unlimited edits, Auto Backup support, and iCloud sync with a Notability subscription Browse notes from the community, search topics/tags, save favorites for later, and download notes Publish notes for the world to see in the Notability Gallery Easily create searchable multi-page PDFs using the built-in Document Scanner Import PDFs, DOCs, PPTs, images, GIFs, and more Create outlines, interactive checklists, and text boxes Full-featured, left-aligned typing with word count and a wide range of fonts, custom fonts, sizes, and colors Quickly switch between notes and Drag & Drop handwriting, typed text, images, etc. Engage an audience with all of Notability's tools including a Laser Pointer Present ideas in full screen without distracting toolbars when connected to an external display ![]() Replay audio recordings and tap anywhere on your note to hear what was said at that moment Quickly switch between ink or eraser styles with the Favorites Toolbar Precisely erase freehand ink or shapes with varied brush sizes Double-tap gesture for switching tools, erasing, and more Ink fine-tuned for the Apple Pencil for the most responsive, precise writing experience yet Group notes with customizable subjects and dividers Continuous page scroll for exploring endless ideas Instantly create notes from a selection of templates with customizable spacing and backgrounds Mark up imported textbooks, documents, lecture slides, class assignments, and images Variety of note-taking, journaling, and drawing tools like ink, highlighter, text, and audio What Our Customers Are Saying About Our Baby Photo Albums You can do all this with our easy-to-use, fun, and friendly software. Feel free to add stickers and to move elements around. Each of them comes in various sizes, so you can go with what feels best for you. Select from portrait, landscape, and square shapes. The choices you have include the shape of the book. You decide how the book is going to look and feel. Or, make it your own by beginning with a blank canvas. If you wish, start with one of our themes. You can change the layout, background, and colors to represent your baby's unique character. Choose templates from our lay flat photo books collection and add elements of the design to give nurture your memories. The best part is, you can create different types of books that are tailor-made to your story. You can then rediscover each moment together. This will ensure that your book lasts long enough for your child to see it when they're old enough. Mixbook baby photo books are made from the highest-quality paper. The first birthday is important as well! You can keep each of those events safely in a baby photo book. Then, you can have an image of their first steps. You can store the day they start to crawl. Then, you can capture your baby's life right from the moment they come into the world. Starting from the pregnancy, a record of each milestone will help preserve how you felt during the period. With a photo book and custom photo cards, you can document every step of the way. You deserve to have a way to keep these memories forever. ![]() Each moment is precious, including all the days preceding the event. There is nothing more special or important than the birth of a child. Make your own photo book by choosing from fully customizable designer baby photo book themes or start with a blank book and create your own using thousands of design elements. Someday, your child will thank you for preserving the memories. ![]() Baby albums make wonderful gifts for godparents, grandparents and great grandparents so that they too can reminisce about those once in a lifetime memories. Your baby album is the place where these precious memories will remain safe. Mixbook’s baby photo books and scrapbook templates offer plenty of room to show off every one of your baby’s milestones. Make sure you take the time to capture and remember the memories in a baby album that’s made to last. Baby Photo Books and Memories Picture Albumīaby’s first year goes by so fast. Whether to stop to save log messages in local buffer after the specified memory-lines number is reached Memory-stop-on-full ( yes|no Default: no) Number of records in local memory buffer, applicable only if action=memory Whether to use tls when sending email, applicable only if action=emailĮmail address where logs are sent, applicable only if action=email Whether to stop to save log messages to disk after the specified disk-lines-per-file and disk-file-count number is reached, applicable only if action=disk Specifies maximum size of file in lines, applicable only if action=disk Name of the file used to store log messages, applicable only if action=diskĭisk-lines-per-file ( integer Default: 100) Specifies number of files used to store log messages, applicable only if action=disk Whether to use bsd-syslog as defined in RFC 3164ĭisk-file-count ( integer Default: 2) system logging add topics=ntp,debug,!packet For example, we want to log NTP debug info without too much details: ![]() '!' character can be used before topic to exclude messages falling under this topic. Log all messages that falls into specified topic or list of topics. ![]() Topics ( account, bfd, caps, ddns, dns, error, gsm, info, iscsi, l2tp, manager, ntp, packet, pppoe, radvd, rip, script, smb, sstp, system, timer, vrrp, web-proxy, async, bgp, certificate, debug, dot1x, dude, event, hotspot, interface, isdn, ldp, mme, ospf, pim, pptp, raw, route, sertcp, snmp, state, telephony, upnp, warning, wireless, backup, calc, critical, dhcp, e-mail, firewall, igmp-proxy, ipsec, kvm, lte, mpls, ovpn, ppp, radius, read, rsvp, simulator, ssh, store, tftp, ups, watchdog, write Default: info) Prefix added at the beginning of log messages Specifies one of the system default actions or user specified action listed in actions menu If print is in follow mode you can hit 'space' on keyboard to insert /log > print follow where topics~".info" For more information about parameters refer to scripting manualįor example following command will print all log messages where one of the topics is info and will detect new log entries until Ctrl+C is /log > print follow where topics~".info" Note: print command accepts several parameters that allows to detect new log entries, print only necessary messages and so on. In example above you can see that second message was added on sep/15 current year (year is not added) and the last message was added today so only the time is displayed. If logs are printed at the same date when log entry was added, then only time will be shown. Sep/15 12:42:14 system,info,account user admin logged in from 10.1.101.212 via telnet ![]() Sep/15 12:35:34 system,info mangle rule changed by admin Sep/15 12:34:29 system,info mangle rule moved by admin Sep/15 12:34:26 system,info mangle rule added by admin Sep/15 12:33:18 system,info item added by admin Sep/15 09:54:33 system,info,account user admin logged in from 10.1.101.212 via winbox Each entry contains time and date when event occurred, topics that this message belongs to and message /log> print Logs can be saved in routers memory (RAM), disk, file, sent by email or even sent to remote syslog server (RFC 3164).Īll messages stored in routers local memory can be printed from /log menu. RouterOS is capable of logging various system events and status information. ![]() The software supports batch movie extracting and converting, thus, you can process all your files at once. You need only select the length of the segment, then add it to the processing list, on the right. You can easily navigate through the DVD contents, thanks to the title and chapter selectors, as well as to the previewing window, that renders synchronized image and sound. You can open and extract video from any chapter from your DVD, including the menu, by setting the start and end point of the segment. ![]() You may also select the output format, between QuickTime movie, AVI, DV stream movie and MPEG-2 Program stream. Similarly, you can save the video, in order to import it to a presentation, or to publish it on the Web, play it on TV or on other portable devices. Cinematize Pro is an useful too for creating a movie trailer. Thus, you can select the high quality output, for a seamless video and audio playback on your computer. Multiple purpose videosĬinematize Pro supports multiple output file types, that define the possibility of further uses, for your video. You can decode the video and audio streams and save them as editable AVI files. ![]() It is a useful tool in converting DVD data for high quality rendering, on the PC or dedicated equipment, as well as for editing. It is capable of processing both video and audio stream and it can extract subtitle segments as well. Powerful extraction toolĬinematize Pro features both flexibility in allowing you to select the video clip, down to seconds, and speed in extracting data from a DVD or recording file. The software enables you to batch extract and process movie segments from discs, Video Recording files and Video Title Sets. An incomplete uninstallation of a program may cause problems, which is why thorough removal of programs is recommended.Cinematize Pro is a comprehensive software that enables you to extract video and audio fragments from DVDs and convert them to different formats, according to your needs. There could be other causes why users may not be able to uninstall Cinematize Pro HD Demo.
![]() Data at 3HR were normalized to baseline values and expressed fold change over baseline in a heat map. Markers that were undetectable were not included in the analysis. Analysis was restricted to N=4 per group due to assay cost. (A) Cytokine and chemokines were quantified in the baseline and 3HR plasma sample by Bio-Plex Pro Rat Cytokine 23-Plex Assay. ![]() Hemorrhagic shock heparan sulfate organ injury thromboinflammation traumatic injury.Ĭopyright © 2023 Vidaurre, Osborn, Lowak, McDonald, Wang, Pa, Richter, Xu, Arnold, Liu and Cardenas.ĭekaparin treatment decreases plasma levels of thromboinflammatory mediators after T/HS. Finally, dekaparin treatment attenuated induction of thrombin-antithrombin complex and inflammatory mediators in plasma following trauma and hemorrhagic shock.Īnti-thromboinflammatory properties of a synthetic 3- O-sulfated heparan sulfate 12-mer, dekaparin, could provide therapeutic benefit for mitigating organ injury following major trauma and hemorrhagic shock. No differences in organ injury, neutrophil infiltrates, or fibrin staining between dekaparin and FFP groups were observed. This was associated with a significant reduction in neutrophil infiltration in lungs and kidneys and reduced lung fibrin deposition among dekaparin-treated rats compared to vehicle. While LR-vehicle-resuscitated rodents exhibited increased lung and kidney injury, administration of dekaparin significantly reduced organ injury scores and was similar to organ protection conferred by FFP resuscitation. Compared to vehicle, dekaparin treatment did not affect induction, severity, or recovery of shock as indicated by hemodynamics, metabolic indicators of shock (lactate and base excess), or metrics of bleeding, including overall blood loss, resuscitation volume, or hematocrit. Induction of trauma and hemorrhagic shock resulted in significant increases in thrombin-antithrombin complex, inflammatory markers, and lung and kidney injury scores. Lungs and kidneys were processed for organ injury scoring and immunohistochemical analysis to quantify presence of neutrophils. Serial blood samples were collected at baseline, after induction of shock, and 3 hours after fluid resuscitation to measure hemodynamic and metabolic shock indicators, inflammatory mediators, and thrombin-antithrombin complex formation. Vehicle and dekaparin-treated rats were resuscitated with Lactated Ringer's solution (LR) and compared to vehicle-treated fresh-frozen-plasma-(FFP)-resuscitated rats. Male Sprague-Dawley rats were pre-treated subcutaneously with vehicle (saline) or dekaparin (2 mg/kg) and subjected to a trauma/hemorrhagic shock model through laparotomy, gut distention, and fixed-pressure hemorrhage. ![]() Our goal was to evaluate therapeutic potential of a synthetic 3- O-sulfated heparan sulfate dodecasaccharide (12-mer, or dekaparin) to attenuate thromboinflammation and prevent organ injury. Endothelial heparan sulfate containing a rare 3- O-sulfate modification on a glucosamine residue is anticoagulant and anti-inflammatory through high-affinity antithrombin binding and sequestering of circulating damage-associated molecular pattern molecules. Heparan sulfates, cell surface glycosaminoglycans abundantly expressed on the endothelial surface, regulate a variety of cellular processes. Dysregulated inflammation and coagulation are underlying mechanisms driving organ injury after trauma and hemorrhagic shock. |
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